Spondylodiscitis — tuberculous or pyogenic

MRI · CT

First and second year — the floor first, then every step

Contrast MRI of the whole spine: find the infected disc and endplates, then the collections and the canal — and read the pattern that separates tuberculosis (disc relatively spared, large paraspinal abscess, skip lesions) from pyogenic infection.

Orient first

  • Pyogenic spondylodiscitis centres on the disc: the disc and the endplates on both sides of it are involved together, early.
  • Tuberculous spondylitis (Pott disease) favours the thoracolumbar junction, spreads under the anterior longitudinal ligament to several levels, relatively spares the disc early, and forms large, thin-walled paraspinal or psoas abscesses, sometimes with skip lesions.
  • The management questions are an epidural collection compressing the cord or cauda equina, instability or kyphosis, and a target for biopsy.

Acquire the study

  • Whole-spine sagittal T1, T2 and STIR screening; axial T2 and post-contrast fat-saturated T1 through affected levels.

The manoeuvre

  • Sagittal STIR of the whole spine: every level with marrow oedema — tuberculosis often involves several or non-contiguous levels.
  • Disc: T2 high signal and enhancement (pyogenic) versus relative preservation with subligamentous spread (tuberculosis).
  • Endplates on T1: loss of the dark cortical line and erosion.
  • Post-contrast T1 fat-saturated: paraspinal and psoas abscess (rim-enhancing), epidural abscess or phlegmon; measure the collection in mm.
  • Canal: degree of cord or thecal sac compression and cord signal change on axial T2.
  • Alignment: vertebral collapse, gibbus and posterior element involvement.

What confirms it

  • Disc and adjacent endplate involvement with enhancement, with or without collections, supporting infection — tissue or culture decides the organism.

What licenses you to exclude it

  • A normal contrast MRI of the whole spine makes spondylodiscitis very unlikely.

The classic misread

  • Calling Modic type 1 degenerative change infection — it lacks disc T2 hyperintensity, enhancement of the disc and collections.

See it on real cases

Direct links to Radiopaedia — the reference article and worked cases with their images. Each opens on Radiopaedia.

Key papers

Reviews and guidelines from RSNA, ESR and related journals. Each opens at its DOI.

  1. Spondylodiscitis: a call for unified guidelines ↗Albano D, Basile M, Sconfienza LM · European Radiology 2026ESR · PubMed
  2. MRI characteristics of tuberculous spondylitis ↗Currie S, Galea-Soler S, Barron D, et al. · Clinical Radiology 2011RCR · PubMed
  3. A diagnostic model for differentiating tuberculous spondylitis from pyogenic spondylitis on computed tomography images ↗Liu X, Zheng M, Sun J, et al. · European Radiology 2021ESR · PubMed
  4. Yield of Image-Guided Needle Biopsy for Infectious Discitis: A Systematic Review and Meta-Analysis ↗McNamara AL, Dickerson EC, Gomez-Hassan DM, et al. · AJNR 2017ASNR · PubMed

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