Gout and calcium pyrophosphate disease

X-ray · USG · CT

First and second year — the floor first, then every step

Gout: punched-out erosions with overhanging edges and tophi, the double-contour sign on ultrasound, urate coloured on dual-energy CT; CPPD: chondrocalcinosis of the menisci and TFCC and the SLAC wrist pattern.

Orient first

  • Gout erosions are juxta-articular with sclerotic overhanging edges; joint space preserved until late.
  • Double-contour sign = urate on the cartilage surface; DECT colour-codes urate (beware artefact at nail beds and skin).
  • CPPD: chondrocalcinosis (menisci, TFCC, pubic symphysis) and degenerative change in unusual joints (radiocarpal, patellofemoral).

Acquire the study

  • Radiographs of the affected joints and both feet.

The manoeuvre

  • Radiograph: punched-out erosions with overhanging edges, first MTP.
  • Tophi on the radiograph: soft-tissue densities, may calcify.
  • Chondrocalcinosis on the knee and wrist radiograph: meniscal and TFCC linear calcification (CPPD).

What confirms it

  • Crystals on joint aspiration; imaging supports when aspiration is not possible.

What licenses you to exclude it

  • No double contour and no DECT urate make gout less likely but do not exclude early disease.

The classic misread

  • Calling tophaceous gout a bone tumour.

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