Reading the uterus on MRI — adenomyosis, fibroids and the junctional zone

MRI

First and second year — the floor first, then every step

The JUNCTIONAL ZONE is the measurement that carries the diagnosis, and it is a T2 finding.

Orient first

  • The uterus has three layers on T2: a bright endometrium, a dark JUNCTIONAL ZONE (inner myometrium), and intermediate outer myometrium. Almost every diagnosis here is a statement about the junctional zone.
  • ADENOMYOSIS is junctional-zone thickening — commonly quoted as abnormal above 12 mm, indeterminate 8–12 mm — with tiny T2-bright myometrial cysts and sometimes T1-bright foci of haemorrhage.
  • A FIBROID is a well-defined, low-T2 mass with a pseudocapsule that DISPLACES the junctional zone; adenomyosis is ill-defined and expands it. That distinction decides between myomectomy and hysterectomy or medical therapy.
  • The junctional zone varies with the cycle and is unreliable in the immediate post-partum period and on hormonal therapy — say what the timing was.
  • Fibroid LOCATION drives management more than size: submucosal (and its degree of intracavitary extension), intramural, subserosal or pedunculated.

Acquire the study

  • High-resolution T2 in three orthogonal planes, aligned to the LONG AXIS of the uterus — an off-axis plane makes the junctional zone unmeasurable.
  • T1 with and without fat suppression to identify haemorrhagic foci and to separate a dermoid.
  • Dynamic post-gadolinium where degeneration, sarcoma or fertility-sparing intervention is in question.
  • Confirm which sequence you are on before judging any signal — see the MRI sequence primer.
  • Note cycle day and hormonal status; both change the junctional zone.

The manoeuvre

  • Measure the JUNCTIONAL ZONE at its thickest point on a true long-axis T2 image, and state where you measured.
  • Assess for tiny T2-hyperintense myometrial cysts and for T1-bright haemorrhagic foci.
  • State whether junctional-zone change is diffuse or focal, and whether it is anterior or posterior.
  • For each significant fibroid: location (submucosal, intramural, subserosal, pedunculated), size, and T2 signal.
  • For a submucosal fibroid, state the PROPORTION protruding into the cavity, which decides hysteroscopic resectability.
  • Assess for degeneration: high T2 signal, absent enhancement, or T1-bright red degeneration.
  • Assess the endometrium, the cavity, and both ovaries.
  • Look for deep infiltrating endometriosis at the torus, uterosacral ligaments and rectovaginal septum if pain is the indication.

What confirms it

  • Junctional-zone thickening beyond the threshold WITH myometrial cysts is characteristic of adenomyosis.
  • A well-defined low-T2 mass with a pseudocapsule displacing rather than expanding the junctional zone is a fibroid.

What licenses you to exclude it

  • A normal-thickness junctional zone on a well-aligned, correctly-timed study makes adenomyosis unlikely.
  • ⚠️ An off-axis or badly-timed study cannot exclude it. State the limitation rather than reporting a normal uterus.
  • MRI cannot reliably exclude leiomyosarcoma. Rapid growth, irregular margins, restricted diffusion and necrosis raise concern, but the report should say that tissue is the arbiter.

The classic misread

  • Measuring the junctional zone on an off-axis plane.
  • Calling focal adenomyosis a fibroid — the pseudocapsule and displaced junctional zone are the discriminators.
  • Not stating intracavitary extension for a submucosal fibroid.

Reference values

Each value carries the caveat that keeps it from being misused. Normal limits and diagnostic criteria are kept apart on purpose: a disease cut-off read as a normal range is the more dangerous mistake.

Diagnostic criteria

  • Uterine junctional zone · Junctional zone thickness (adenomyosis)

    up to 8 mm is conventionally normal; 12 mm or more supports adenomyosis, with 8–12 mm equivocal

    The junctional zone thickens transiently with contractions and varies with the cycle and hormonal state — an equivocal measurement on one sequence deserves a second look later in the study. Focal T2 hyperintense myometrial foci support the diagnosis at any thickness.

    MRI

  • Myometrium (adenomyosis) · Adenomyosis signs beyond junctional-zone thickness

    myometrial cysts, fan-shaped shadowing, an irregular JZ, and T2-bright foci. The registered JZ band is the companion number: up to 8 mm conventionally normal, 12 mm or more supports adenomyosis, 8–12 mm equivocal — signs can support the diagnosis at any thickness

    Contractions thicken the JZ and mimic adenomyosis. Focal adenomyoma versus myoma is a T2 / vessel-margin conversation, not a millimetre. Versioned criterion — verify against the current edition before clinical use.

    USG · MRI

  • Uterine leiomyoma · FIGO leiomyoma location 0–8

    0–2 submucosal (0 pedunculated intracavitary, 1 <50% intramural, 2 ≥50% intramural). 3–5 intramural (3 contacts endometrium, 4 entirely intramural, 5 subserosal ≥50% intramural). 6–7 subserosal (6 <50% intramural, 7 pedunculated). 8 other (cervical, parasitic). Type, not a remembered cc, drives the procedure talk — same map as the FIGO-named companion

    Location, not size, decides hysteroscopic versus abdominal approaches. A "3 cm fibroid" without a FIGO number is an incomplete report for a procedural question. Versioned criterion — verify against the current edition before clinical use.

    USG · MRI

See it on real cases

Direct links to Radiopaedia — the reference article and worked cases with their images. Each opens on Radiopaedia.

Key papers

Reviews and guidelines from RSNA, ESR and related journals. Each opens at its DOI.

  1. Imaging Spectrum of Typical and Atypical Adenomyosis ↗Brandão A, Oliveira BC, Ferreira IAG, et al. · RadioGraphics 2025RSNA · PubMed
  2. European Society of Urogenital Radiology (ESUR) Guidelines: MR Imaging of Leiomyomas ↗Kubik-Huch RA, Weston M, Nougaret S, et al. · European Radiology 2018ESR · PubMed
  3. MRI characteristics of the uterine junctional zone: from normal to the diagnosis of adenomyosis ↗Novellas S, Chassang M, Delotte J, et al. · AJR 2011ARRS · PubMed
  4. MRI-based pictorial review of the FIGO classification system for uterine fibroids ↗Gomez E, Nguyen MT, Fursevich D, et al. · Abdominal Radiology 2021SAR · PubMed

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