The second-trimester anomaly scan

USG

First and second year — the floor first, then every step

A protocol-driven survey where completeness is the product — the views are prescribed, and what you did not see must be reported.

Orient first

  • This is a SURVEY, not a targeted study. Its value comes from doing the same prescribed views every time, so that an abnormality is found by protocol rather than by suspicion.
  • The highest-yield sections are the ones most often abbreviated: the four-chamber view AND the outflow tracts, the posterior fossa, the upper lip, and the spine in three planes.
  • DETECTION RATES ARE NOT 100% for any structure, and vary with gestation, habitus, position and liquor. That is a property of the test, and the report should not imply otherwise.
  • Many anomalies EVOLVE. A normal scan at 20 weeks does not exclude a lesion that will declare itself at 28 — coarctation, some cerebral and renal anomalies, and bowel pathology in particular.
  • A SOFT MARKER is not an anomaly. Its significance depends entirely on prior risk and on whether it is isolated, and reporting one without that framing causes avoidable alarm.

Acquire the study

  • Curvilinear abdominal probe; transvaginal for a low-lying fetal head or a difficult cervix.
  • Confirm gestational age from the earliest available measurement — biometry interpretation depends on correct dating, not on today's measurements.
  • Work through the prescribed view list in a fixed order, and document each view.
  • If a view cannot be obtained, reposition the mother, walk her, and rescan before concluding — and if it still cannot be obtained, record it as not seen.

The manoeuvre

  • Confirm number, viability, presentation and placental site, and describe the cord insertion.
  • HEAD: measure BPD, HC; assess the ventricular atrium, cavum septi pellucidi, midline falx, and the posterior fossa including the cerebellum and cisterna magna.
  • FACE: profile, orbits, and a clear view of the UPPER LIP.
  • SPINE: longitudinal, transverse and coronal, with the overlying skin intact.
  • HEART: situs and axis, four-chamber view, LEFT and RIGHT outflow tracts, the three-vessel and three-vessel-trachea views.
  • ABDOMEN: measure AC; stomach on the left, kidneys, bladder, cord insertion, and the diaphragm as an intact line.
  • LIMBS: measure femur length; confirm all long bones and both hands and feet with their orientation.
  • Measure liquor volume and, where indicated, the cervix.
  • Record explicitly which prescribed views were NOT obtained.

What confirms it

  • A complete study is one in which every prescribed view was obtained and documented — completeness IS the finding.

What licenses you to exclude it

  • ⚠️ A NORMAL ANOMALY SCAN DOES NOT EXCLUDE AN ANOMALY. State the detection limitation plainly rather than issuing a report that reads as an all-clear.
  • Views not obtained must be listed, with a plan to repeat — an incomplete study reported without that list is the most common failure here.
  • Reduced liquor, maternal habitus and fetal position each degrade sensitivity; say which applied.

The classic misread

  • Reporting a study as complete when views were missed.
  • Assessing the heart on the four-chamber view alone, which misses outflow tract anomalies.
  • Reporting an isolated soft marker without the prior-risk framing.

Reference values

Each value carries the caveat that keeps it from being misused. Normal limits and diagnostic criteria are kept apart on purpose: a disease cut-off read as a normal range is the more dangerous mistake.

Normal limits

  • Fetal biometry · BPD, HC, AC and FL — the four standard parameters

    score BPD, HC, AC and FL millimetres in the Fetal Growth calculator (INTERGROWTH-21st, Papageorghiou Lancet 2014 Table 2), or paste a machine centile from another named chart

    BPD and HC on a transventricular axial plane showing the cavum septi pellucidi and thalami, outer-to-inner for BPD. AC on an axial plane at the level of the stomach and the umbilical portion of the left portal vein, with no kidneys visible. FL along the ossified diaphysis excluding the epiphyses.

    ⚠️ READ AGAINST A DATED PERCENTILE CHART, not a single number: the value changes with gestation and the reference population differs between charts. State which chart was used. ⚠️ THE PLANE IS THE MEASUREMENT. An AC taken one rib space too high reads small and will manufacture growth restriction across serial scans. Report the plane adequacy as well as the value.

    USG

  • Cisterna magna · Cisterna magna depth

    2–10 mm in the second trimester — score the millimetre in the calculator

    Axial transcerebellar plane. Measured from the posterior vermis to the inner table of the occipital bone.

    Above 10 mm indicates megacisterna magna and warrants assessment of the vermis for Dandy–Walker continuum abnormalities; below 2 mm raises an open neural tube defect with the banana sign. ⚠️ An oblique plane falsely enlarges it.

    USG

Diagnostic criteria

  • Fetal lateral ventricle · Atrial width of the lateral ventricle

    under 10 mm throughout the second and third trimesters — score the millimetre in the calculator

    Axial transventricular plane. Measured at the level of the glomus of the choroid plexus, perpendicular to the ventricular axis, inner-to-inner.

    Notably STABLE across gestation, which is why it is a fixed number where most fetal measurements are curves. 10–12 mm is mild ventriculomegaly, 12–15 mm moderate, above 15 mm severe. ⚠️ Measure the FAR ventricle — the near one is obscured by reverberation artefact.

    USG · MRI

  • Nuchal fold · Nuchal fold thickness, 15–20 weeks

    under 6 mm at 15–20 weeks — score the millimetre in the calculator

    Axial transcerebellar plane showing the cavum, cerebellum and cisterna magna. Measured from the outer edge of the occipital bone to the outer skin surface.

    ⚠️ DISTINCT FROM NUCHAL TRANSLUCENCY, which is a FIRST-trimester measurement with a different plane, technique and threshold — the two are frequently confused and are registered separately. Valid only within the stated gestational window.

    USG

See it on real cases

Direct links to Radiopaedia — the reference article and worked cases with their images. Each opens on Radiopaedia.

Key papers

Reviews and guidelines from RSNA, ESR and related journals. Each opens at its DOI.

  1. ISUOG Practice Guidelines (updated): performance of the routine mid-trimester fetal ultrasound scan ↗Salomon LJ, Alfirevic Z, Berghella V, et al. · Ultrasound in Obstetrics & Gynecology 2022ISUOG · PubMed
  2. How to apply the 20 + 2-planes method for identification of 65 fetal abnormalities during routine second-trimester fetal ultrasound examination ↗Chudleigh T, Cohen-Overbeek TE · Ultrasound in Obstetrics & Gynecology 2025ISUOG · PubMed

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