Metastatic spinal cord compression

MRI

First and second year — the floor first, then every step

Image the WHOLE spine, find every level, and state the highest level with cord signal change — the clinical level is often wrong.

Orient first

  • Cord compression is a time-critical diagnosis: the neurological state at the moment of treatment is the strongest predictor of the outcome, so speed of reporting matters as much as accuracy.
  • Metastatic disease is frequently at MULTIPLE levels, and a second lesion above the clinical level changes the radiotherapy field or the surgical plan. This is why the whole spine is imaged, not the symptomatic region.
  • The clinically-determined sensory level is unreliable and is often several segments away from the true compressive level.
  • Below the conus the problem is cauda equina compression, not cord compression, and the anatomy and urgency wording differ.

Acquire the study

  • MRI WHOLE SPINE — cervical, thoracic and lumbosacral — sagittal T1 and sagittal T2 or STIR as the minimum. STIR is the sequence in which marrow disease shouts.
  • AXIAL sequences through every abnormal level; the degree of canal and cord compromise cannot be judged on sagittals alone.
  • Contrast is not required to make the diagnosis but helps with intradural or leptomeningeal disease.
  • If MRI is contraindicated, say so and recommend CT myelography rather than reporting a CT as equivalent.

The manoeuvre

  • Scroll the whole sagittal T1 for marrow replacement — metastases are LOW signal against normally fatty adult marrow, and T1 is the most reliable screening sequence.
  • Compare with STIR, where disease is high signal.
  • At every abnormal level, assess epidural soft tissue, the degree of thecal sac indentation, and whether the cord is deformed or merely abutted.
  • Look for CORD SIGNAL CHANGE (high T2 within the cord) — this indicates myelopathy and carries prognostic weight.
  • State the HIGHEST level of compression and list every other involved level.
  • Assess vertebral body height loss, posterior wall retropulsion and pedicle involvement — these drive stability assessment.
  • Distinguish benign osteoporotic collapse from malignant: benign tends to spare the pedicles, show a fluid sign and a retropulsed fragment with preserved marrow; malignant shows complete marrow replacement, a convex posterior wall, pedicle involvement and an epidural soft-tissue mass.
  • Look at the conus level to decide cord versus cauda equina.

What confirms it

  • Epidural tumour indenting the thecal sac with cord deformity is cord compression.
  • Cord signal change indicates established myelopathy and should be stated explicitly.

What licenses you to exclude it

  • A whole-spine MRI with normal marrow, no epidural disease and a normal cord excludes metastatic cord compression.
  • ⚠️ A study limited to the symptomatic region does not exclude disease elsewhere, and must say so rather than being reported as a normal spine.

The classic misread

  • Imaging only the clinically suspected region.
  • Missing a second, higher level of compression.
  • Not stating whether there is cord signal change.
  • Calling a benign osteoporotic fracture malignant, or the reverse — check the pedicles and the marrow.

Reference values

Each value carries the caveat that keeps it from being misused. Normal limits and diagnostic criteria are kept apart on purpose: a disease cut-off read as a normal range is the more dangerous mistake.

Normal limits

  • Spinal cord · Anteroposterior cord diameter, cervical and thoracic

    the cord tapers from cervical enlargement to thoracic; compare with adjacent levels rather than quoting a single millimetre for the whole cord

    A universal "normal cord is X mm" is wrong at most levels. Myelomalacia is volume LOSS plus T2 signal; swelling is the acute-injury / inflammatory pattern.

    MRI

  • Thoracic spinal cord · Thoracic cord bulk relative to the cervical enlargement

    the cord tapers below the cervical enlargement; a thoracic cord that is bulkier than the cervical cord is swollen until proven otherwise

    Compare levels on the same sagittal. A "normal thoracic millimetre" copied from a cervical table is a wrong number.

    MRI

See it on real cases

Direct links to Radiopaedia — the reference article and worked cases with their images. Each opens on Radiopaedia.

Key papers

Reviews and guidelines from RSNA, ESR and related journals. Each opens at its DOI.

  1. Nontraumatic Spinal Cord Compression: MRI Primer for Emergency Department Radiologists ↗Laur O, Nandu H, Titelbaum DS, et al. · RadioGraphics 2019RSNA · PubMed
  2. Spinal Metastasis Reporting: Evidence-Based Recommendation on Behalf of the American Society of Spine Radiology Education and Standards Committee ↗Eldaya RW, Ali S, Hadi M, et al. · AJNR 2026ASNR · PubMed
  3. Multidisciplinary management of spinal metastases: what the radiologist needs to know ↗Bahouth SM, Yeboa DN, Ghia AJ, et al. · British Journal of Radiology 2022BIR · PubMed
  4. Spinal metastasis: diagnosis, management and follow-up ↗Mossa-Basha M, Gerszten PC, Myrehaug S, et al. · British Journal of Radiology 2019BIR · PubMed

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